KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
34.24
Human Site:
Y953
Identified Species:
47.08
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
Y953
L
V
N
E
G
F
E
Y
R
L
R
E
I
C
K
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
Y953
L
V
N
E
G
F
E
Y
R
L
R
E
I
C
K
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
Y1074
L
V
N
E
G
F
E
Y
R
L
R
E
I
C
K
Dog
Lupus familis
XP_543550
1017
111618
Y953
L
V
N
E
G
F
E
Y
R
L
R
E
I
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
Y951
L
V
N
E
G
F
E
Y
R
L
R
E
I
C
K
Rat
Rattus norvegicus
NP_001129232
1015
111665
Y951
L
V
N
E
G
F
E
Y
R
L
R
E
I
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
Y959
L
V
N
E
G
F
E
Y
R
L
R
E
L
C
K
Frog
Xenopus laevis
Q8QFR2
1013
112021
Q949
L
V
N
E
G
F
E
Q
R
L
R
E
V
C
Q
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
H946
L
V
N
E
G
Y
E
H
R
L
R
E
L
C
Q
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
Y961
L
V
N
E
G
S
E
Y
R
L
R
E
L
C
K
Fruit Fly
Dros. melanogaster
O17468
1047
113397
L971
S
S
S
S
T
S
S
L
S
V
P
Q
P
A
P
Honey Bee
Apis mellifera
XP_001122939
838
91355
I792
H
T
S
A
S
K
S
I
W
D
P
L
I
L
G
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
G889
L
N
D
L
S
R
S
G
A
P
M
Q
V
C
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
S918
L
K
E
D
I
L
P
S
M
A
S
N
R
K
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
A974
E
Y
E
D
V
E
T
A
D
P
A
P
K
G
S
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
H794
I
L
N
G
Q
P
I
H
G
N
K
V
R
I
N
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
T952
I
G
A
E
N
Q
K
T
K
V
E
E
L
L
N
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
93.3
80
73.3
86.6
0
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
93.3
20
13.3
33.3
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
0
6.6
13.3
P-Site Similarity:
N.A.
13.3
N.A.
6.6
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
6
0
0
0
6
6
6
6
0
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
65
0
% C
% Asp:
0
0
6
12
0
0
0
0
6
6
0
0
0
0
0
% D
% Glu:
6
0
12
65
0
6
59
0
0
0
6
65
0
0
0
% E
% Phe:
0
0
0
0
0
48
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
6
0
6
59
0
0
6
6
0
0
0
0
6
12
% G
% His:
6
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
6
0
6
6
0
0
0
0
42
6
0
% I
% Lys:
0
6
0
0
0
6
6
0
6
0
6
0
6
6
42
% K
% Leu:
71
6
0
6
0
6
0
6
0
59
0
6
24
12
0
% L
% Met:
0
0
0
0
0
0
0
0
6
0
6
0
0
0
0
% M
% Asn:
0
6
65
0
6
0
0
0
0
6
0
6
0
0
12
% N
% Pro:
0
0
0
0
0
6
6
0
0
12
12
6
6
0
6
% P
% Gln:
0
0
0
0
6
6
0
6
0
0
0
12
0
0
18
% Q
% Arg:
0
0
0
0
0
6
0
0
59
0
59
0
12
0
0
% R
% Ser:
6
6
12
6
12
12
18
6
6
0
6
0
0
0
6
% S
% Thr:
0
6
0
0
6
0
6
6
0
0
0
0
0
0
0
% T
% Val:
0
59
0
0
6
0
0
0
0
12
0
6
12
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
6
0
48
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _